Is Daily Aspirin Right for You?

by Dr. Stephen Sinatra 

Early in my career when I was running through hospital halls, coat tails flying behind me, headed to help someone in cardiac arrest—I pondered whether daily aspirin could prevent these types of calamities. It was the 1980s and there wasn’t a hard-working doctor who didn’t worry about having their own heart attack. Knowing that aspirin had the power to thin the blood, many doctors began adding a daily aspirin to their regimen.

Later on, once the efficacy was confirmed, it was decided an 81 mg baby aspirin could replace the hefty 325 mg adult dose. Bayer, the largest producer of aspirin, jumped at the chance to promote its pain reliever as the “wonder drug” in heart attack prevention, even in healthy individuals. Doctors began prescribing it to virtually every patient they had.

Daily Aspirin Increases Bleeding Events

Now, a new meta-analysis of 9 placebo-controlled trials challenges that practice. This month, the Archives of Internal Medicine published data collected from 100,000 people over six years showing that we have to treat 120 people with a daily aspirin to prevent just one nonfatal myocardial infarction (MI).

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The researchers did report that total cardiovascular events decreased by 10 percent.  But at the same time there was a 30 percent increased risk for “trivial bleeding events.”  Because it took treating just 73 people to trigger that bleeding event, we must think twice about our overzealous use of aspirin.

The Bottom Line on Daily Aspirin 

* I don’t recommend an aspirin for primary heart attack prevention. While a daily aspirin prevents clot formation, the final step that triggers a heart attack, it doesn’t change atherosclerotic plaque which is the underlying cause of heart disease.

A far better way to prevent a heart attack is by keeping plaque from forming and building up in the first place.  That means back to basics: a healthy diet, exercise, weight reduction, nutritional support with antioxidants and anti-inflammatories, blood pressure lowering, stress reduction
and so on.

* But taking a daily aspirin for secondary heart attack prevention—if you’ve already had a heart attack or have a history of cardiovascular disease—is just plain good medicine. I regularly advocate aspirin for those who have known heart disease, such as a history of angina, heart attack, angioplasty or stent procedures, or coronary artery bypass surgery. In these cases, I recommend taking one baby aspirin daily.

But even if you have all the characteristics I just mentioned that would make you a perfect candidate for a daily preventative aspirin regimen, it won’t do you a lick of good if you’re part of the population known as “aspirin-resistant.” Fortunately, there’s a test to determine if an aspirin a day will work for you.

Healthy Skin From Within

Healthy Skin From Within

Studies support the idea that nourishing the skin via dietary supplementation yields positive results.by Robert M. Blair , Ph.D., Strategic Research Scientist

Healthy Skin From Within

While it is important to take care of our skin the summer with the application of topical products, taking care of our skin by consuming skin-healthy foods and supplements is also important.  Some of the more amusing ingredients to keeping your skin looking and feeling healthy this summer include Pycnogenol, vitamin C, resveratrol and hyaluronic acid.

Pycnogenol 

A number of studies have shown that Pycnogenol can support normal skin health. One of the early studies on Pycnogenol reported that supplementation for eight weeks helped the skin resist effects of ultraviolet rays, suggesting that it can help protect the skin from sunburn.  Another study reported that consumption of Pycnogenol helped to improve skin hydration and elasticity in postmenopausal women. This was possibly due to an observed increase in the expression of genes involved in the synthesis of collagen.

Vitamin C

Vitamin see is an antioxidant vitamin that is essential for collagen formation. A recent study reported that consumption of Vitamin C could increase the skins ability to scavenge oxidative free radicals, with a dose of 100 mg vitamin C/day increasing this ability by 22% any dose of 180 mg/day increasing this ability by 37 percent.  A population-based study reported that higher vitamin C consumption was associated with a lower likelihood of a wrinkled appearance and reduce skin dryness with age.  Combining vitamin C supplementation with vitamin D supplementation has been reported to reduce the skins sensitivity to sunlight.  

Resveratrol

Resveratrol is a naturally occurring compound found in various fruits, nuts, and berries, but is most abundant in the skin and seeds of grapes.  It is April antioxidant it has been reported to have numerous potential health benefits including skin health benefits.  Several in vitro and animal studies have reported that resveratrol can suppress UV – induced skin damage when applied topically; however, few clinical studies have examined the skin health benefits of resveratrol supplementation.  In one recent study, supplementation with a blend of grape extract (containing 8 mg resveratrol) and pomegranate extract for 60 days resulted in an increase in the skin hydration and elasticity and decrease in skin roughness and wrinkle depth.

Flawless Skin From Within

Hyaluronic acid

Hyaluronic acid is one of the major skin matrix substances in which many of the skin's components ( cells, collagen, a lasting, etc.) are embedded, giving structure to the skin.  The loss of hyaluronic acid as we age is thought to be partly responsible for wrinkle formation and the loss of elasticity as we get older. To date only a few studies have examined the benefit of dietary consumption of hyaluronic acid on skin appearance; however, the study suggested consumption of hyaluronic acid might help hydrate the skin and give it a smoother appearance.  A small pilot study demonstrating that the consumption of a blend of a hydrolyzed collagen type two, low – molecular – wait hyaluronic acid, and chondroitin sulfate lead to a reduction in skin dryness and a reduction in the appearance of wrinkles.

While all of these ingredients are excellent choices for supporting healthy summer skin from within, they are also excellent choices to look for in your topical skin care products. Pre-clinical and clinical studies suggest Pycnogenol, vitamin C, and resveratrol can have anti-aging benefits for the skin and protect the skin from UV induced damage, while hyaluronic acid has been shown to help moisturize the skin at low doses. Combining a topical and dietary approach with skin-healthy ingredients is the ideal approach in order to deliver these ingredients to all the layers of the skin.   Learn more here 

New research exposes risk of nutritional
deficiencies in obese teenagers
by Nathan Gray

Teenagers and young adults who are severely obese are at risk of nutritional deficiencies including low iron, anaemia, and a low vitamin D status, find researchers.

The study is believed to be the first study to compare the nutritional status of severely obese teens who did not undergo weight loss surgery to those who did have surgery ­ finding that at leastyears after undergoing gastric bypass surgery, teens and young adults maintained significant weight loss but were at risk of nutritional deficiencies, particularly low iron, mild anemia and low vitamin D.

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The team, led by Dr Stavra Xanthakos, director the Surgical Weight Loss Program for Teens at Cincinnati Children's, also found low iron and low vitamin D in severely obese teens who did not undergo weight loss surgery. Those who didn't have surgery also had low levels of protein in their blood.

"We knew there were nutritional difficulties in teens who had undergone bariatric surgery, but everyone thought it was primarily the surgery that caused these problems since gastric bypass excludes the portion of the small intestine where many nutrients, especially iron, are most absorbed," said Xanthakos.

"What this shows us is that nutritional deficiencies occur even in teens who don't undergo surgery. Severely obese patients should be screened for nutritional deficiencies, regardless of whether they've undergone weight loss surgery."

Research details
The researchers studied 79 obese teens who either received weight loss surgery or were evaluated but did not receive surgery. These participants were evaluated between 2001 and 2007 and contacted to participate in the study between 2011 and 2014.

Eight years on average after surgery, the team found that the patients had experienced "durable and significant" weight loss, about 28%, while those who didn't receive surgery had not lost weight.

However, both groups were at risk from nutritional deficiencies, said the team ­ who presented their data at the annual meeting of the Pediatric Academic Societies in Vancouver, Canada.

Indeed, obese teens were found to be at risk from low iron and vitamin D irrespective of whether they received the surgery.

The power of Pycnogenol Infographic

The power of Pycnogenol Infographic

• Controlling diabetes
• Relieving arthritis
• A healthier heart

7% reduction of LDL bad cholesterol in young healthy adults after six weeks

5.3 reduction fasting blood glucose levels in type two diabetes patients after three weeks

55% of osteoarthritis patients reported decreased pain after three months

10% increase of HDL good cholesterol in young healthy adults after six weeks

56% of osteoarthritis patients who improved physical functions after three months

53% of osteoarthritis patients reported decreased joint stiffness after three months

57% of individuals who cut blood pressure medication in half after eight weeks

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