The Science and
Advantage of Isotonix
Healthy supplementation is about more than just ingredients; it’s about delivery and absorption. by Dr. Jim Wilmer
The Advantage
The Advantage
When we eat food, drink a beverage, or ingest most nutritional supplements, the stomach must secrete diluting juices, enzymes, hydrochloric acid and at least one vitamin-binding protein to begin the process of digestion. This process requires both energy and time — about 40 minutes or more, depending on the size of the meal. Isotonix products are delivered into the small intestine nutritionally concentrated, maximizing the opportunity for absorption of nutrients across cell membranes.
What Is Isotonic?
Isotonix® is a word, and that’s all to a lot of people. What does it mean? Broken down to its roots, “iso” means “the same” and “tonic” means “pressure” or “tone.” When isotonic is used to describe solutions for human consumption, it means having the same fluid pressure as body fluids. Tears, blood, plasma, lymph and other body fluids are all isotonic.
Isotonix® is a word, and that’s all to a lot of people. What does it mean? Broken down to its roots, “iso” means “the same” and “tonic” means “pressure” or “tone.” When isotonic is used to describe solutions for human consumption, it means having the same fluid pressure as body fluids. Tears, blood, plasma, lymph and other body fluids are all isotonic.
When we ingest food, gastric (or stomach) juice is secreted onto the food and muscular contractions of the stomach mix the contents until a reasonably uniform solution is achieved. The solutions of food (or chyme) that enter the small intestine for absorption are made isotonic by the action of the stomach in a time-consuming process. The fluid pressure of food or isotonic solutions across semi-permeable membranes, such as the walls of the small intestine, is generally referred to as having a particular osmolarity or tonicity. It can be said that when solutions on opposite sides of the membrane have the same osmolarity, they are iso-osmotic or iso-tonic. Normal human blood serum (the fluid portion without cells and platelets) has an osmolarity of 288mOs/kg, as do most other fl uids in the body. Therefore, in physiological terms, when a solution’s osmolarity is the same, or nearly the same, as that of normal human blood serum, it is referred to as isotonic.
Why is gastric emptying so important? The answer is simply this: the longer the supplements stay in the stomach, the longer the time before absorption can begin, because no appreciable absorption occurs from the stomach. Why is gastric emptying time stressed when talking about Isotonix? Because the fastest emptying time occurs when isotonic solutions enter the stomach. When the biological sensors in the gastrointestinal tract detect that the ingested solution is isotonic and at a correct pH, the pyloric or duodenal valve at the lower end of the stomach remains open and the solution is squirted into the small intestine. Absorption of the nutrients by the intestinal mucosa then starts to occur.
Concentration and Absorption
Concentration and absorption are factors that go hand in hand for the proper use of nutritional supplements. Concentration, the amount of nutrient dissolved in a given amount of solution, is directly related to the efficiency of nutritional absorption. It is known that the greater the concentration (as milligrams of nutrient per milliliter of solution at the absorption site), the greater
the rate and amount of absorption. Because Isotonix solutions experience little dilution in the gastrointestinal tract, they arrive at the absorption sites in high concentration to assure effi cient absorption. Isotonix®
Jim L. Wilmer, Ph. D. is Chief Science Officer at Market America and has been employed by the company for over 15 years. He earned a doctorate from Cornell University in environmental toxicology (1991), a master of science in biolog y from East Tennessee State University (1974), and a bachelor of science from Wofford College (1972). Dr. Wilmer has 44 peer-reviewed publications in journals, including Cancer Research, Journal of Investigative Dermatology, Mutation Research, Environmental Mutagenesis, Cell Biology and Toxicology, Cytogenetics and Cell Genetics, Angiology, and Phytotherapy Research.
Jim L. Wilmer, Ph. D. is Chief Science Officer at Market America and has been employed by the company for over 15 years. He earned a doctorate from Cornell University in environmental toxicology (1991), a master of science in biolog y from East Tennessee State University (1974), and a bachelor of science from Wofford College (1972). Dr. Wilmer has 44 peer-reviewed publications in journals, including Cancer Research, Journal of Investigative Dermatology, Mutation Research, Environmental Mutagenesis, Cell Biology and Toxicology, Cytogenetics and Cell Genetics, Angiology, and Phytotherapy Research.
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