Sunday, September 04, 2011

Side Effects of Statin Drugs - Heart Health Nutrition | Dr. Sinatra

Side Effects of Statin Drugs - Heart Health Nutrition | Dr. Sinatra

Side Effects of Statin Drugs

Wednesday, February 2, 2011 by Stephen Sinatra
Despite positive results in some patients, I’m troubled by several aspects of statin drugs, the powerful medication usually prescribed to help you maintain good cholesterol levels.side effects of statin drugs

The most common side effects reported by statin users are:
  • Muscle pain and weakness;
  • Flu-like symptoms; and
  • Generalized soreness.

Other side effects of statins include: liver dysfunction with elevation of the liver enzymes; problems of the nervous system such as a condition called peripheral neuropathy or polyneuropathy; and total global amnesia, which means forgetting where and who you are for a few minutes to several hours. (If LDL cholesterol levels get too low, they can interfere with neurotransmitter mechanisms in the brain.)

One of the many problems with statins is that they interfere with the body’s production of CoQ10, a natural substance that’s absolutely essential for cellular energy production. Such interference causes fatigue, muscle pain, and, as a Swiss study showed, subtle muscle cell damage—even without symptoms.

Given that the heart is made of muscle tissue, it’s not much of a stretch to think these drugs could lead to diastolic dysfunction and, subsequently, congestive heart failure. Research appears to verify the connection between statins, depletion of CoQ10, and congestive heart failure.

I would never take a statin without the added insurance of supplemental CoQ10. Anyone taking a statin drug for an appropriate reason should be chasing it down with a minimum of 200 mg of hydrosoluble CoQ10.

Adhering to a smart cholesterol lowering diet, like the PAMM diet I talk about so frequently, is a wonderful way to maintain healthy cholesterol. You’d be surprised by how just eating the right foods can help you lower your LDL cholesterol levels, while you increase HDL cholesterol levels.

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Monday, August 29, 2011

Study: Green Tea; a long- term solution to immune suppressing drugs in autoimmune disease

Posted by Katie McKeown ND on Sat, 08/27/2011

     A new study from the Linus Pauling Institute at Oregon State University has shown that one of the compounds in green tea (EGCG) greatly increases important immune cells that help in the suppression of autoimmune disease.  An estimated 4.5 million Canadians suffer from autoimmune diseases ranging from rheumatoid arthritis to lupus.   The majority of conventional treatments currently available have long-term side effects due to toxicity and greatly suppress the immune system, leaving patients susceptible to a variety of viral and bacterial infections.  The new study shows that 50 mg/kg of green tea derived EGCG has the ability to increase regulatory T cells in mice, which improve the function of the immune system without the negative effects.
     The immune system is typically a tightly controlled process where a variety of immune cells work together to destroy unwanted invaders without damaging normal cells.  This is regulated by a specific group of cells, including regulatory T cells, which turn the attacking cells on and off when an invader is present.  In autoimmune disease, the process becomes dysfunctional and the attacking immune cells begin destroying healthy, normal cells.  The resulting wide-spread inflammation in the body is what causes the symptoms of autoimmune disease.  By affecting the expression of certain transcription factors of DNA, EGCG has been shown to greatly increase the number of regulatory T cells, thus controlling the immune response and reducing inflammation.
     Conventional immune-suppressing drugs are pivotal in the short-term treatment of autoimmune disease and flare-ups and these results do not alter the need for or use of these drugs.  It is the long-term toxicity effects that researchers and clinical practitioners alike are searching for.  This study has given new hope for a long-term treatment for autoimmune disease that has fewer risks and side effects.  In addition, the exciting new research from Oregon State University gives us more evidence that using dietary supplements and plant-based medicine can not only reduce symptoms but also act directly on DNA expression and alter the course of these debilitating diseases.

Immunology Letters
Volume 139, Issues 1-2, 30 September 2011, Pages 7-13



http://www.sciencedirect.com/science/article/pii/S0165247811001258